It is not likely that new prospective randomized studies will be performed in the future. Therefore, we must live with the data we have. It has not been proven that GH treatment triggers rejection episodes in stable patients. Similarly, no study demonstratingGH-triggered rejection episodes has been published for short children after liver transplantation. Renal patients who respond to steroid avoidance and grow well do not require GH treatment. But how should we proceed in nongrowing, short, transplanted patients? Patients with chronic rejection or repeated rejection episodes are at risk of new episodes with or without GH treatment. An increased risk
with GH is not proven but cannot be ruled out, either. If there is a risk at all, it will be small.