Green Chemistry insists that our synthetic objectives areachieved while assuming additional considerations related to the unnecessary environmental burden created during operations. If using a toxic reagent, one should inquire if a less toxic reagent might accomplish similar ends. A literature search may provide no current alternative with similar efficiency and reduced toxicity, but many do not realize that the simple act of inquiry toward reduced toxicity already indicates a new priority and intent, a higher level of awareness and environmental stewardship, and is Green Chemistry! In some cases a safer reagent will exist. Application will improve the process environmental profile and reduce risk related to working with a toxic reagent while maintaining or improving synthetic efficiency. Some believe an environmental priority will add time and cost. Just the opposite, time and cost are reduced by incorporating higher synthetic efficiency the first time, and new methods can be applied toward parallel and future endeavors to enhance overall productivity.