In a study by Sine Sepehr et al (2012), authors investigated cytotoxic and apoptotic effects of PPE and PSE extract of Iranian Pomegranate on proliferation of PC-3 cells. In this study, PPE caused to the maximum growth inhibition of 65% at doses 600μg/ml while PSE caused to no significant growth inhibition on proliferation of PC-3 cells. Pomegranate seed extract (PSE) at the highest dose (600μg/ml) caused to maximum growth inhibition of 35%. In our experiment, at dose 250μg/ml, PPE and PSE caused to the maximum growth inhibition of 84.16% and 85.37%, respectively, values comparable to 20μg/ml Toxol which suppressed 93.1% growth inhibition of PC-3 cells.