Besides its use in cosmetics,2-Bromo-2-nitropropane-1,3-diol has a number of approved use areas,including FDA-regulated adhesives and as slimicide in the paper industry and in paper coatings.EPA registrations have been issued for a number of material protection industries.It is approved for water treatment and for the paper industry in many European countries.Japan has approved its pharmaceutical use as a wound irrigating solution.Cosmetic industry registration in Japan is pending .