Bites from most (non-poisonous) spiders cause local redness, irritation, and pain that usually can be treated at home using an over-the-counter pain reliever along with application of cooling packs or a wet cloth to relieve swelling. These local reactions usually resolve without treatment over a period of 7-10 days. Rarely, an individual can have an allergic reaction to a spider bite, even to a bite from a non-poisonous spider, but allergic reactions are more likely to be due to contact with a spider than from a spider bite.