While keeping a reasonable agreement with the experimental data from literature (free cell cultures with/without cell membrane permeabilization), the structured model advantages are coming from the prediction detailing degree [simulated 26 + 3 (cell + bulk) vs. 3 (bulk) variable dynamics] covering a wide range of input Hg2+ loads (0–100 mg L−1), and cloned
E. coli cells with various amounts of mer-plasmids (3–140 nM).