Methods: Five iso-caloric diets, denriche with liquid (in water 30% vol/vol) or solid (in diet 65% g/g) fructose or sucrose or a
control diet were fed for eight weeks to C57bl/6 mice. Sugar, liquid and caloric intake, small intestinal sugar transporters
(GLUT2/5) and weight regulating hormone mRNA expression, as well as hepatic fat accumulation were measured. In obese
versus lean humans that underwent either bariatric surgery or small bowel resection, we analyzed small intestinal GLUT2,
GLUT5, and cholecystokinin expression.