INTRODUCTION
Proteases execute a large variety of functions and have important biotechnological applications.
Proteases represent one of the three largest groups of industrial enzymes and find application in
detergents, leather industry, food industry, pharmaceutical industry and bioremediation processes
[1]. Proteases are widespread in nature, microbes serve as a preferred source of these enzymes
because of their rapid growth, the limited space required for their cultivation and the ease with
which they can be genetically manipulated to generate new enzymes with altered properties that
are desirable for their various applications [2] Bacillus produces a wide variety of extra-cellular
enzymes, including proteases. Several Bacillus species involved in protease production are e.g.
B. cereus, B. sterothermophilus, B. mojavensis, B. megaterium and B. Subtilis [3-8]
F Soundra Josephine et al J. Microbiol. Biotech. Res., 2012, 2 (1):163-168
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