The program’s focus on model building provided students with powerful insight into structure/function relationships and the diversity of chemical architectures. The hands‐on aspect of the class at the outset, as well as the fact that the students were aware that they were learning “college‐level” science, made the experience highly enjoyable and empowering. Finally, the curriculum featured 3D computer molecular modeling (PyMol, Schrödinger LLC), which allowed students to apply their knowledge of organic chemistry to biomolecules such as enzymes and DNA that would be too large to build with the handheld models. Altogether, the curriculum contrasts traditional science learning frameworks and is intended to go beyond current science standards. The impressive student results described below are the result of only 3.5 hours of instruction, so it is exciting to imagine what kinds of student achievement would be possible with a multi‐year expansion of this curriculum.