UVC-Induced CellularLesions
Two major UV-induced lesion mechanisms in cells form CPDs
and/or 6–4 photoproducts(6–4PPs) and their valence isomers. These are the principal lesions leading to mutagenesis.
The formation of 6–4PPs also may result in changes in cell
metabolism as they can inhibitor induce other combined
cytotoxic effects.