Increasing the concentration of iodide results in a
reduction in the amount of free iodine in the solution;
the level of free iodine determines its antiseptic function.
The combination of iodine-based substances with
hydrogen peroxide might be advantageous. The combination
of PVP-I and hydrogen peroxide exerted synergistic
bactericidal effects against periodontal pathogens,113-115
allowing Maruniak et al,116 in 1992, to
conclude that a significant reduction effect occurs
against dental plaque and gingivitis using the combination
of iodine and hydrogen peroxide.
Although most investigators agree prevention is
better than treatment, none of the isolated preventive
methods has been successful or achieved total acceptance.
Most physicians still use their own methods,
which are usually the topical antimicrobial agents
used for other maxillofacial infections, usually without
any scientific studies to confirm the effectiveness
for the treatment of dry socket.1 One example is the
use of irrigation with 2% sodium iodide plus 3% hydrogen
peroxide for the treatment of patients hospitalized
with osteoradionecrosis caused by radiotherapy,
which resulted in the best clinical outcomes
compared with other treatments, including surgical
debridement.117,118 This irrigation solution, because
of its antianaerobic property, was effective in the
areas infected by these microorganisms.
Increasing the concentration of iodide results in areduction in the amount of free iodine in the solution;the level of free iodine determines its antiseptic function.The combination of iodine-based substances withhydrogen peroxide might be advantageous. The combinationof PVP-I and hydrogen peroxide exerted synergisticbactericidal effects against periodontal pathogens,113-115allowing Maruniak et al,116 in 1992, toconclude that a significant reduction effect occursagainst dental plaque and gingivitis using the combinationof iodine and hydrogen peroxide.Although most investigators agree prevention isbetter than treatment, none of the isolated preventivemethods has been successful or achieved total acceptance.Most physicians still use their own methods,which are usually the topical antimicrobial agentsused for other maxillofacial infections, usually withoutany scientific studies to confirm the effectivenessfor the treatment of dry socket.1 One example is theuse of irrigation with 2% sodium iodide plus 3% hydrogenperoxide for the treatment of patients hospitalizedwith osteoradionecrosis caused by radiotherapy,which resulted in the best clinical outcomescompared with other treatments, including surgicaldebridement.117,118 This irrigation solution, becauseof its antianaerobic property, was effective in theareas infected by these microorganisms.
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