In hypertension, the release of contracting factors is increased due to an up-regulation of endothelial Ca2þ signalling. In the arteries of Vitamin D deficient rats, there is an increase in the basal tone of the mesenteric arteries.
In hypertension, the release of contractingfactors is increased due to an up-regulation of endothelial Ca2þsignalling. In the arteries of Vitamin D deficient rats, there is anincrease in the basal tone of the mesenteric arteries.