The wettability of both the flat Al-PDMS-DOPA-pSB and the micropatterned Al-PDMS-DOPA-pSB coatings was also examined with water contact angle measurements (Fig. 4). The contact angle of the flat Al-PDMS-DOPA coatings is ∼96◦, much lower than that of the flat Al-PDMS coatings (∼118◦). This result agrees well with a previous study that water contact angle of the samples decreased significantly after DOPA modification [27]. However, the flat Al- PDMS-DOPA-pSB displays a hydrophilic property with a water contact angle of ∼32◦, which is predominately due to the wettable nature of the zwitterionic polymer pSB layer. This is consistent with previous studies that zwitterionic structure exhibits high hydrophilicity [26]. The micropatterned coating samples exhibit similar tendency (Fig. 4), once again confirming successful fab- rication of the flat Al-PDMS-DOPA-pSB and the micropatterned Al-PDMS-DOPA-pSB.