The greatest benefit of the physicochemical-based methodes is the short time required for treatment. However, alternatives are being considered as a result of the limited reduction of organic matter and the production of a large amount of harmful sludge by these processes. Large organic matter concentrations are good conditions for the growth and development of microorganisms. The removal of color and COD can be controlled with flexibility with the operating parameters of bioreactors and the adaptable conditions of microorganisms such as A. terreus SA3 and Stenotrophomonas AAP56. Some species of fungi and bacteria have used and show a high capability for biosorption of sulfer dyes or dyes wastewater;