Alkaloids are important chemical compounds that serve as a rich reservoir for drug discovery. Several alkaloids isolated from
natural herbs exhibit antiproliferation and antimetastasis effects on various types of cancers both in vitro and in vivo. Alkaloids,
such as camptothecin and vinblastine, have already been successfully developed into anticancer drugs. This paper focuses on the
naturally derived alkaloids with prospective anticancer properties, such as berberine, evodiamine, matrine, piperine, sanguinarine,
and tetrandrine, and summarizes the mechanisms of action of these compounds. Based on the information in the literature that
is summarized in this paper, the use of alkaloids as anticancer agents is very promising, but more research and clinical trials are
necessary before final recommendations on specific alkaloids can be made
Alkaloids are important chemical compounds that serve as a rich reservoir for drug discovery. Several alkaloids isolated fromnatural herbs exhibit antiproliferation and antimetastasis effects on various types of cancers both in vitro and in vivo. Alkaloids,such as camptothecin and vinblastine, have already been successfully developed into anticancer drugs. This paper focuses on thenaturally derived alkaloids with prospective anticancer properties, such as berberine, evodiamine, matrine, piperine, sanguinarine,and tetrandrine, and summarizes the mechanisms of action of these compounds. Based on the information in the literature thatis summarized in this paper, the use of alkaloids as anticancer agents is very promising, but more research and clinical trials arenecessary before final recommendations on specific alkaloids can be made
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ลคาลอยด์เป็นสารประกอบทางเคมีที่สำคัญที่ทำหน้าที่เป็นอ่างเก็บน้ำที่อุดมไปด้วยสำหรับการค้นพบยาเสพติด Alkaloids are important chemical compounds that serve as a rich reservoir for drug discovery. Several alkaloids isolated from
natural herbs exhibit antiproliferation and antimetastasis effects on various types of cancers both in vitro and in vivo. Alkaloids,
such as camptothecin and vinblastine, have already been successfully developed into anticancer drugs. This paper focuses on the
naturally derived alkaloids with prospective anticancer properties, such as berberine, evodiamine, matrine, piperine, sanguinarine,
and tetrandrine, and summarizes the mechanisms of action of these compounds. Based on the information in the literature that
is summarized in this paper, the use of alkaloids as anticancer agents is very promising, but more research and clinical trials are
necessary before final recommendations on specific alkaloids can be made
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