Fig. 3. Time-trends of the identified TPs for (a) bezafibrate, (b) carbamazepine, (c) diclofenac, (d) furosemide, (e) hydrochlorothiazide, (f) ibuprofen, (g) metoprolol, (h)propranolol. Dashed curves in plot (a) and (g) indicate that these compounds are shown on the secondary vertical axis.