Discussion
In the present study, streptozotocin was used to induce experimental diabetes in the rats. Streptozotocin can prevent DNA synthesis in the mammals and bacterial cells. In the bacterial cells,it can lead to a special reaction with cytosine groups, resulting in degeneration and destruction of DNA. Mammalian cell death is owing to its biochemical mechanism. Streptozotoc in can pre-vent cellular reproduction with the less doses needed for inhibiting the substrate connection to the DNA or inhibiting several enzymes involved in DNA synthesis [12].The level of blood sugar before and after diabetes induction and body weight one day before, at the day o, and one day after diabetes induction were measured. There was an increase in blood sugar and the decrease in the rat’s weight. Comparing the pancreas of the diabetic and normal rats, the Langerhans islets and beta cells of thediabetic rats were clearly destructed.In this research, PVA/chitosan nanofibers used as the wounddressing.In spite of investigating the effect of different nanofibersparticularly PVA/chitosan nanofibers on wound healing, thepresent study is the first study evaluating diabetic wound healing