GME-loaded nanoparticles possessed a spherical
shape (Figure 4A and 4B) with hydrodynamic size around
625.4 ± 19.6 nm and zeta potential of -3.6 ± 0.2 mV (Table
1). It was obvious that the encapsulated GME dispersed
well in water while the unencapsulated GME showed
poor water dispersibility (Figure 4C). With the loading of
almost 50% (w/w), the GME-loaded particles showed
excellent water dispersibility because all the hydrophobic
GME molecules were at the inside of the nanoparticles.
The outer surface of the particles probably contained
hydrophilic hydroxyl moieties which interacted we