owning to the lower oxygen concentration in the fluid surrounding the chondroblasts an increase in their produce of procollagen will occur increased amounts of collagen will become deposited in the matrix.progressive converting the previous hyaline material into fibrocartilage.the chondroblasts may respond to their reduced ability to secrete adequate amounts of specific glycoprotein by undergoing a process of cellular proliferation cell division increases the number of cells capable of secreting the nesessary material and increases the surface to volume ratio of the secretory mass.in older cartilage the cell cluster each contain more cell than in younger specimens.as the nutrient supply to these degeneration cells become worse death and disintegration of the chondroblasts may follow leaving empty cavities within the cartilage.