and toxicogenomics will allow for faster toxicity screening [21,23]. Designing substances where worker exposure is a possibility needs to include consideration of uncertainty around estimates because one chemical may be more green in one metric and less so in another [24]. Still, tools like EPA’s software called T.E.S.T (toxicity estimates software tool) can assist the chemical industry with development of green chemistry alternate products and processes by predicting toxicity of materials which could have an impact on workers’ safety and health as well [25].