A survey approach was adopted to investigate the strategic use of e-business by SMEs in the region. The activities of such SMEs are quite diverse, reflecting the economic characteristics of each county. Cambridgeshire has a dynamic and fast growing economy with a cluster of advanced high technology and biotechnology businesses around the University of Cambridge Science Parks. Essex contains a broad range of businesses that benefit from proximity to London and good transportation links. Norfolk and Suffolk are less industrial. Small to mid-sized businesses in those counties have traditionally served the retail, agricultural, leisure and tourism industries.