hypertensive patients, aldosterone receptor antagonists decrease blood pressure to limit end-organ damage. Eplerenone improves arterial compliance and reduces vascular stiffness by decreasing the collagen-to-elastin ratio.32 Both spironolactone and eplerenone have been shown to decrease left ventricular mass with a reduction in the prevalence of hypertrophy in treated patients from 30% to 7%.33, 34