human impact on
Gastrointestinal problems, such as constipation , diarrhea , poor appetite , or weight loss , are common in acute poisoning. Absorption of large amounts of lead over a short time can cause shock (insufficient fluid in the circulatory system ) due to loss of water from the gastrointestinal tract. Hemolysis (the rupture of red blood cells ) due to acute poisoning can cause anemia and hemoglobin in the urine . Slow development of normal childhood behaviors, such as talking and use of words, and permanent intellectual disability are both commonly seen.