Fig. 1. (A) Structure of KN. (B) Effects of KN on total BMD of rats (n = 8). (C1–C5) Micro CT scan
of right femur of the rats in each group (n = 3): C1-Sham group; C2-OVX group;
C3-EV group; C4-KH group; C5-KL group. The OVX rats showed a notable decrease in BMD and the
trabecular area. KN-treated and EV-treated groups partially prevented OVX- induced bone loss and
significantly improved the microarchitecture after 12 weeks treatment. ∗∗ P < 0.01 vs. OVX group; ##
P < 0.01 vs. Sham group.