Due to fundamental differences in the laboratory methods and medication regime, the results of the three studies regarding the effect of clopidogrel on equine ADP-induced platelet function are
not comparable. A disaggregation phenomenon detected by use of ADP-induced optical aggregometry in platelet-rich plasma (PRP), as described in dogs treated with clopidogrel (Brainard et al., 2010),
was not seen in our study with horses using ADP-induced whole blood impedance aggegometry.