Replication dynamics of phage in vitro. The replication dynamics
of each candidate phage were determined in vitro at
MOIs of 100, 103, and 106 prior to application in vivo. Both the
optical density and plate count data indicated that the number
of bacteria of each Salmonella serotype was reduced appreciably
in the presence of phage at each MOI after 24 h (Fig. 2).
When the highest MOI was used, S. enterica serotype Enteritidis
P12509, Hadar 18, and Typhimurium 4/74 numbers were