CONCLUSIONS
The applying of Gagne's instructional design on CAL
can improve the ability of learners in problem analysis,
which consists of several adjusted components, these are
(1) giving the clearly learning objectives, (2) explaining
the objectives in the beginning, (3) giving the concept
map of learning materials, (4) providing free learning
sequence, (5) giving the learning content briefly, (6)
describing the learning material verbally and completely,
(7) presenting the learning material with animations, (8)
using pictures or video. It is important to motivate
students by providing CAL that uses multimedia
principles, convenient interface, and easy to use
navigation. Beside those, for developing self-directed
learning culture, it is important in each topic should
provide exercises to measure the student learning
progress. Finally, the alimentary CAL modules can
enhance the analytical skills of students in PBL with effect
size 0.89 (big effect category). It proved that the selfdirected
learning culture in medical student successfully
implemented. The experimental group can improve their
analytical skill without any assistance or intervention by
the lecturers.