In conclusion, this trial demonstrates that chitosan does
not have a clinically significant effect on weight loss or other
measured outcomes in overweight and obese men and
women taking a dose of 3 g/day. No increase in faecal fat
excretion was observed to support the putative mechanism
of action of chitosan, and treatment is associated with some
minor gastrointestinal side effects. It therefore seems appropriate
to focus public attention on the proven effective
means of weight loss such as improved nutrition and
increased physical activity.