These observations seem to be
linked with changes in patterns of endometrium gene
expression mediated by the energetic status of the cows.
Wathes et al. (2009) evaluated global gene expression
of the endometrium of cows at 2 weeks postpartum.
They reported that several probes linked with
inflammation and active immune response were still
upregulated in cows undergoing severe NEB compared
with those exhibiting a more modest caloric deficit,
suggesting a delay in uterine involution.