Totally 15 proteins were involved in carbon metabolic pathway. Moreover, contents of 37 metabolites including amino acids, organic acids, sugars, and sugar alcohols were regulated by drought and salt treatments. Among them, 18 commonly modulated metabolites were involved in carbon and amino acid metabolic pathways. Drought treatment for 21 days caused less accumulation of sugars and sugar alcohols and increased ROS level in bermudagrass which led to relatively more severe cell membrane reflected by high EL-value and lower survival rate when compared to 400 mM salt treatment for 21 days. These results suggested that drought and 400 mM NaCl stresses for 21 days treatment affected common and specific changes in bermudagrass, which would provide new insights to understand the underlying molecular mechanisms and metabolic homeostasis of bermudagrass in responses to abiotic stresses.