To the best of the authors’ knowledge, there are some methods investigating PFAS concentrations in dairy and human milk[5,15,18–21]; yet detailed characterization and descriptions of method parameters was limited to two of them [5,15].This study describes a new and easy LC/ESI–MS/MS methodfor the determination of 12 perfluorinated acids in milk. In particular we developed an enrichment method using graphitized carbon black (GCB) which may allow the selective isolation of analytes target from complexes matrices thanks to the various types of interactions (hydrophobic, electronic and ion-exchange) with analytes. GCB sorbents have been applied in various enrichmenttechniques, particularly in SPE