Thirty-six patients were randomized to receive
lansoprazole and 34 patients to receive omeprazole. Ten
of the 36 (29%) patients treated with 30 mg lansoprazole
once daily and 23 of the 34 (68%) patients
treated with 20 mg omeprazole once daily had persistently
abnormal re¯ux at oesophageal pH monitoring
(P < 0.001).