Phages were used to treat several enteric diseases, such as
cholera and dysentery, during the 1920e40s. They were also used
for food and agriculture applications. For example, d’Herelle
showed that Salmonella Gallinarum, the bacteria responsible for
avian typhoid, was sensitive to phage treatment (Summers, 2012).
Although early phage therapy had some success, treatments had
varying results and were often not repeatable. With the development
of more chemical antimicrobials, the use of phage therapy
declined during the mid-1900s in the western hemisphere (Harper
and Kutter, 2008). However, the emergence of multiple drug
resistant bacteria has caused a revived interest in phage therapy
research.