Management
Treatment of cholecystitis depends on the severity of the condition and the presence or absence of complications.
For acute cholecystitis, initial treatment includes bowel rest, IV hydration, correction of electrolyte abnormalities, analgesia, and IV antibiotics. Options include the following:
Sanford guide – Piperacillin-tazobactam, ampicillin-sulbactam, or meropenem; in severe life-threatening cases, imipenem-cilastatin
For cases of uncomplicated cholecystitis, outpatient treatment may be appropriate. The following medications may be useful in this setting:
Levofloxacin and metronidazole for prophylactic antibiotic coverage against the most common organisms
Antiemetics (eg, promethazine or prochlorperazine) to control nausea and prevent fluid and electrolyte disorders
Analgesics (eg, oxycodone/acetaminophen)