Dogs with congestive heart failure (CHF; group C) had significantly higher CRP concentrations (median, 2.65 mg/L; quartile 1–quartile 3, 1.09–5.09) compared to dogs in groups A (median, 0.97 mg/L; quartile 1–quartile 3, <0.50–1.97; P = 0.001), B1 (median, 0.78 mg/L; quartile 1–quartile 3, <0.50–1.73, P < 0.0001) and B2 (median, 0.60 mg/L; quartile 1–quartile 3, <0.50–1.23; P < 0.0001). Other variables reflecting disease severity, including left atrial to aortic root ratio (P = 0.0002, adjusted r2 = 0.07) and left ventricular end-diastolic diameter normalised for bodyweight (P = 0.0005, adjusted r2 = 0.06), were positively associated with CRP concentration, but the association disappeared if dogs with CHF were excluded from analysis. In conclusion, slightly higher CRP concentrations were found in dogs with CHF whereas severity of asymptomatic MMVD showed no association with CRP concentrations.
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