Indeed, Fig.1B shows that commercial LPC, at 10 mMalso
protected retinal ganglion cells from death. On the other
hand, higher concentrations of LPC (up to 25 mM) led cells
to death, being considered toxic on such concentrations;
while at lower concentrations (5 mM), LPC was ineffective
upon ganglion cells (Fig. 1B). It is worthwhile emphasizing
that a synergic effect between LPC (5 mM or 10 mM) and
fatty acids (10 mM) upon ganglion cells survival was not
observed (data not shown). Moreover, fatty acids alone (5–
50 mM) also did not interfere on ganglion cell survival;
neither stimulated nor inhibited (data not shown).