The hydroalcoholic extract of C. asiatica showed anxiolytic/sedative effect in elevated plus maze, potentiation of the hypnotic effect of pentobarbitone and anticovulsant activity against pentylenetetrazol-induced convulsion. The oral LD50 of the extract in rats was found to be higher than 675 mg/kg, indicating a high therapeutic index. In addition, chronic oral administration also exhibited a low toxicity for C. asiatica.