2.4. Statistical analyses
For each tissue, the correlation between gene expression level of tumorsuppressorgenesandcompositional features of CDSs and proteins was analyzed with MINITAB and GraphPad. P-Values below 0.01 were considered significant. However, in some tissues, because of the lack of p-value less than 0.01, we considered the characteristics with p-values below 0.05 as themost significant features. Finally, to pinpoint which features are truly significant, Bonferroni correction was done to decrease the statistical errors. Bonferroni correction was taken into account for each parameter separately by SISA program (http://www.quantitativeskills. com/sisa/calculations/bonhlp.htm)withthe α-value = 0.05 in the whole correlation analyses.