The interaction of nanomaterials with cells and lipid bilayers is
critical in many applications such as phototherapy, imaging, and
drug/gene delivery. These applications require a firm control
over nanoparticle–cell interactions, which are mainly dictated by
surface properties of nanoparticles. This critical Review presents
an understanding of how synthetic and natural chemical
moieties on the nanoparticle surface (in addition to nanoparticle
shape and size) impact their interaction with lipid bilayers and
cells. Challenges for undertaking a systematic study to elucidate
nanoparticle–cell interactions are also discussed.
Effect of Surface Properties on Nanoparticle–Cell Interactions
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