The current study demonstrates the superior effect of high-intensity aerobic exercise on aerobic capacity, endothelial function, insulin action, lipogenesis, and improvement of the cardiovascular risk profile in rats with the metabolic syndrome, when compared with a moderate-intensity exercise programme.
The study presents novel mechanistic insights into the causes of the differential effects of high- and moderate-intensity exercise training programmes and how they may correct metabolic and vascular abnormalities associated with the metabolic syndrome.