An estimated two billion people live in areas at risk of malaria with blood stage of the parasite responsible for malaria-associated pathology [1].
In malaria-endemic regions, uncomplicated and severe malaria exists with the former being highly prevalent.
Parasite load of more than 100,000 parasites/μL of blood are commonly regarded as indicators of risk of severe malaria in a low-transmission setting [2].
Symptoms of uncomplicated malaria may include fever, althralgia, headache, pallor, liver enlargement (mild hepatomegaly) and spleen enlargement (mild splenomegaly); and any of these could present at any stage of infection.
However, since the aforementioned symptoms are non-specific for malaria, WHO recommends that malaria parasite confirmation in blood film through microscopy should be mandatory especially in endemic regions where these symptoms are mostly perceived to be solely caused by malaria and thereby given to arbitrariness and self medication [3].
Most times, among malarial-infected population, symptomaticand asymptomatic individuals are represented with the later largely due to the protective effect of the immune system following a repertoire of infection