In case of dissolution in simulated saliva, dissolution profile of
pitaya powder effervescent tablet was not significantly different
from pineapple powder effervescent tablet at two, three, four, and
5 min. Pitaya and guava powder effervescent tablet profiles were
shown no significant difference at one, three and 4 min; same
phenomenon was also happened in case of pitaya powder and
mango powder effervescent tablet for four, five and 6 min steps; in
case of pineapple and guava powder effervescent tablet at one, two
and 3 min steps; in case of pineapple and mango powder effervescent tablet at four, five and 6 min steps; and for guava and mango powder effervescent tablet at two and 5 min steps. However, the dissolution profiles of fruit powder effervescent tablets
were significantly different from each other to the other at the time
steps, excluding these time steps in individual case. In both dissolution mediums, a pairwise dissolution profile comparison shows
that the dissolution profiles were not different or same at all the
time steps. O'Hara et al. (1998) reported the dissolution profile may
be considered to differ significantly from each other if the error bars
at each dissolution time point do not overlap. Dissolution profiling
results from, Figs. 2 and 3 it is observed that at most of the dissolution time points error bars were not overlapped. So, according to
statistical method dissolution, profiles were significantly different
from each other at most of time points.