Anti- atherogenic, renoprotective and immune modulatory activity
Rasha and Lamiaa43 had reported the efficiency of purslane (components of ω-3 and ω-6) on hyperlipidemia, kidney function and as
immunomodulators in rats fed high cholesterol diets. The present study showed that 2% cholesterol administration caused a significant increase in total
cholesterol, total lipids and triacylglycerol in both serum and liver. Serum phospholipid, LDL-C, and atherogenic index (AI) also significantly increased
compared to control group. Cholesterol-enriched diet significantly increased serum urea,creatinine , sodium and potassium levels as well as significantly
increased serum IgG and IgM compared to healthy control. Consumption of purslane by hypercholesterolemic rats resulted in a significantly decrement in
lipid parameters and significant improvement in IgG and IgM levels as compared with hypercholesterolemic rats. This result suggests that purslane had antiatherogenic
hypolidermic and immunomodulatory effects which were probably mediated by unsaturated fatty acids (including alpha linolenic acid) present
in seed mixture.