The purposes of this research were (1) to build and to find the quality of learning-teaching on Information technology and data communication and computer network system with Web Quest lesson of Matthayomsuksa 2 (2) to study the efficiency by applying teaching by using the problem as base with Web Quest lesson having the efficiency no less than criterion 80/80 (3) to study learning achievement of learner beforehand after receiving learning-teaching on Information Technology and data communication and computer network system with Web Quest lesson of Matthayomsuksa 2 and (4) to evaluate the satisfaction to learning-teaching on Information Technology and data communication and computer network system with Web Quest lesson.