Overall, transplantation remains the best option for patients with HCC. Unfortunately, there is a limited supply of good-quality deceased donor organs. Thus, alternative treatments, including resection, radiofrequency ablation (RFA), and, potentially, systemic therapy with sorafenib, should be used to bridge patients to transplant or to delay recurrence if possible. In patients who experience a recurrence following resection or transplantation, aggressive surgical treatment appears to be associated with the best possible outcome.[32]