The construction industry in Hong Kong heavily relies on conventional cast in-situ construction involving extensive use of timber formworks and wet trades. In 2001, the Construction Industry Review Committee (CIRC) report described the construction activities in Hong Kong as 'labour intensive, dangerous and polluting', in which 'built products are rarely defect-free'. Globally, however, the recent trend is prefabrication, which is being increasingly used in the building industry, alleviating some of the environmental burdens associated with conventional construction. The sustainable construction aspects of adopting prefabrication in high-rise buildings are examined, and the economic, environmental and social aspects of using prefabrication are assessed. A questionnaire survey was administered to experienced professionals and case studies of seven recent residential and non-residential buildings in Hong Kong were conducted. The findings revealed that environmental, economic and social benefits of using prefabrication were significant when compared to conventional construction methods. This implies that a wider use of prefabrication techniques could contribute to sustainable construction in a dense urban environment like Hong Kong. [PUBLICATION ABSTRACT]