To clarify the generating mechanism of the 2011 Tohoku-oki earthquake (Mw 9.0) and the induced tsunami, we determined high-resolution tomographic images of the Northeast Japan forearc. Significant lateral variations of seismic velocity are visible in the megathrust zone, and most large interplate thrust earthquakes are found to occur in high-velocity (high-V) areas. These high-V zones may represent high-strength asperities at the plate interface where the subducting Pacific plate and the overriding Okhotsk plate are coupled strongly. A shallow high-V zone with large coseismic slip near the Japan Trench may account for the mainshock asperity of the 2011 Tohoku-oki earthquake. Because it is an isolated asperity surrounded by low-velocity patches, most stress on it was released in a short time and the plate interface became decoupled after the Mw 9.0 earthquake. Thus the overriding Okhotsk plate there was shot out toward the Japan Trench and caused the huge tsunam