Phase 3 (multiorgan dysfunction) and distant compli-cations: Organ disorders may develop a few hours after the onset of symptoms or later, including ARDS (Acute Respiratory Distress Syndrome) and/or kidney dysfunction. ARDS is known as a noninfectious inflammatory process of small bronchi accompanied by exudate to the lumen of the pulmonary alveoli; the originating hyaline membranes interfere with gas exchange. Renal dysfunction, previously called the lower nephron syndrome, is kidney reaction to hypovolemia; reduced diuresis is the first signal of renal dysfunction.