The divergent results reported in these two recent studies suggest that the performance of mixtures strongly depends on the specific strain of Saccahromyces and non-Saccahromyces yeast species. Considering the good yield of mezcal 75Sc/25Td, its richness in minor compounds, and its performance in sensory tests, it could been suggested that there is a synergistic interaction betweenS. cerevisiaeITD-00185 and T. delbrueckiiITD-00014a at the proportions used in this mixture.