a. Bio technique was introduced about thirty years ago by European and American surgeons to treat patient born with physical disabilities. In 1986, a company from the Netherlands, called Uroplasty in the Netherlands applied Micro Implant Injection Technique to produce a silicon filler called "Bioplastique". his substance was initially employed to treat damaged vocal cords or the urethral sphincter, but it soon outshone fat and collagen as an injectable filler and has been widely used in Thailand since 2000. October 2005) (Excerpted from COMPASS Magazine. Vol.3, No.29